Relative contribution of cytochromes P-450 and flavin-containing monoxygenases to the metabolism of albendazole by human liver microsomes. Journal Article


Authors: Rawden, Helen C.; Kokwaro, Gilbert O.; Ward, Stephen A.; Edwards, Geoffrey
Article Title: Relative contribution of cytochromes P-450 and flavin-containing monoxygenases to the metabolism of albendazole by human liver microsomes.
Keywords: ALBENDAZOLE; MICROSOMES
Journal Title: British Journal of Clinical Pharmacology
Volume: 49
Issue: 4
ISSN: 03065251
Publisher: Wiley-Blackwell  
Date Published: 2000-04
Start Page: 131
DOI/URL:
Notes: --- - Article - Investigates the sulphoxidation of albendazole (ABZ) in human liver microsomes and recombinant systems. Effect of selective chemical inhibitors on ABZ sulphoxidation; Capability of cytochromes and monoxygenases to mediate sulphoxide metabolite formation (ABS); Metabolism rate of ABZ to ABS in human liver microsomes. - ! 'Accession Number: 6018055; Rawden, Helen C. Kokwaro, Gilbert O. Ward, Stephen A. Edwards, Geoffrey; Source Info: Apr2000, Vol. 49 Issue 4, p131; Subject Term: ALBENDAZOLE; Subject Term: MICROSOMES; Number of Pages: 10p; Illustrations: 8 Graphs; Document Type: Article'
SU Authors
  1. Prof. Gilbert Kokwaro
    26 Kokwaro